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Fentanyl and Metabolite, Serum or Plasma, Quantitative
Ordering Recommendation
Use to monitor patient adherence.
New York DOH Approval Status
Specimen Required
Plain red, lavender (K2EDTA), lavender (K3EDTA), green (sodium heparin), gray (potassium oxalate/sodium fluoride), or pink (K2EDTA).
Separate from cells ASAP or within 2 hours of collection. Transfer 4 mL serum or plasma to an ARUP standard transport tube. (Min: 2 mL)
Refrigerated.
Whole blood. Serum separator tubes, light blue (sodium citrate), or plasma separator tubes. Specimens exposed to repeated freeze/thaw cycles.
Ambient: 1 week; Refrigerated: 2 weeks; Frozen: 3 years
Methodology
Quantitative Liquid Chromatography-Tandem Mass Spectrometry
Performed
Tue, Thu, Sat
Reported
1-8 days
Reference Interval
Effective August 17, 2015
| Drugs Covered | Cutoff Concentrations |
| Fentanyl | 0.1 ng/mL |
| Norfentanyl | 0.1 ng/mL |
Interpretive Data
Methodology: Quantitative Liquid Chromatography-Tandem Mass Spectrometry
Positive cutoff: 0.1 ng/mL
For medical purposes only; not valid for forensic use.
The absence of expected drug(s) and/or drug metabolite(s) may indicate noncompliance, inappropriate timing of specimen collection relative to drug administration, poor drug absorption, or limitations of testing. The concentration value must be greater than or equal to the cutoff to be reported as positive. Interpretive questions should be directed to the laboratory.
Laboratory Developed Test (LDT)
Note
Hotline History
Hotline History
CPT Codes
80354 (Alt code: G0480)
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 2011777 | Fentanyl, S/P, Quant | 3636-8 |
| 2011782 | Norfentanyl, S/P, Quant | 11074-2 |
Aliases
- Actiq
- Duragesic
- Durogesic
- Fentanyl and Metabolite
- fentanyl and norfentanyl blood levels
- Fentore
- Innovar
- Instanyl
- Ionsys
- norfentanyl
- Onsolis
- pain management
- Sublimaze
